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Design of antiseptic formulations containing extract of Plinia cauliflora BJPS
Oliveira,Lara Alexandre de; Souza-Moreira,Tatiana Maria de; Cefali,Letícia Caramori; Chiari,Bruna Galdorfini; Corrêa,Marcos Antonio; Isaac,Vera Lucia Borges; Salgado,Hérida Regina Nunes; Pietro,Rosemeire Cristina Linhari Rodrigues.
The leaves of the Brazilian species Plinia cauliflora were used to obtain active hydroalcoholic extract and fractions enabling the development of efficient antiseptic pharmaceutical formulations. A chemical composition of 70% ethanol extract, aqueous and ethyl acetate fractions was analyzed by thin-layer chromatography and for phenol content. Antimicrobial activity was tested against Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Lactobacillus acidophilus and Candida albicans by the agar diffusion method and the minimum inhibitory concentration was assayed by broth microdilution. Extract microbiological quality was tested to avoid contamination in the formulations. A mouthwash and a topical cream containing the extract were developed...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antiseptic formulations/design; Plinia cauliflora/antimicrobial activity; Plinia cauliflora/antiseptic activity; Mouthwash; Plant extract; Topical cream.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000300010
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Development and validation of a microbiological assay for determination of chlorhexidine digluconate in aqueous solution BJPS
Fiorentino,Flávia Angélica Másquio; Corrêa,Marcos Antonio; Salgado,Hérida Regina Nunes.
Chlorhexidine (CHX) is a broad-spectrum antiseptic that is used in many topical pharmaceutical formulations. Because there is no official microbiological assay reported in the literature that is used to quantify CHX, this paper reports the development and validation of a simple, sensitive, accurate and reproducible agar diffusion method for the dosage of chlorhexidine digluconate (CHX-D) in an aqueous solution. The assay is based on the inhibitory effect of CHX-D upon the strain of Staphylococcus aureus ATCC 25923, which is used as the test microorganism. The design 3x3 parallel-line model was used. The results were treated statistically by analysis of variance (ANOVA), and they were excellent in terms of linearity (r = 0.9999), presenting a significant...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Agar diffusion; Antiseptic; Chlorhexidine; Microbiological assay; Quality control; Validation.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000200017
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Guava: phytochemical composition of a potential source of antioxidants for cosmetic and/or dermatological applications BJPS
Chiari-Andréo,Bruna Galdorfini; Trovatti,Eliane; Marto,Joana; Almeida-Cincotto,Maria Gabriela José de; Melero,Ana; Corrêa,Marcos Antonio; Chiavacci,Leila Aparecida; Ribeiro,Helena; Garrigues,Teresa; Isaac,Vera Lucia Borges.
ABSTRACT Guava (Psidium guajava L.) is a native fruit of the American tropics with commercial applications for its taste, flavor and aroma. Numerous pharmacological uses have been described for it, such as the antiseptic effect of its leaves, the use of the fresh fruit and tea from its leaves for the treatment of diarrhea, dysentery, diabetes mellitus, and others. However, considering its rich composition, the guava also is a potential source of antioxidants to be used in the development of new formulations for cosmetic and/or dermatological applications, the main focus of this research. Herein, we describe the study of the phytochemical composition and the antioxidant activity of a guava extract prepared with non-toxic solvents aiming its use at...
Tipo: Info:eu-repo/semantics/article Palavras-chave: P. guajava L./phytochemistry; P. guajava L./use in cosmetics; P. guajava L./antioxidant/chemical composition; P. guajava L/chemical stability; High Performance Liquid Chromatography.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000200612
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Inorganic UV filters BJPS
Manaia,Eloísa Berbel; Kaminski,Renata Cristina Kiatkoski; Corrêa,Marcos Antonio; Chiavacci,Leila Aparecida.
Nowadays, concern over skin cancer has been growing more and more, especially in tropical countries where the incidence of UVA/B radiation is higher. The correct use of sunscreen is the most efficient way to prevent the development of this disease. The ingredients of sunscreen can be organic and/or inorganic sun filters. Inorganic filters present some advantages over organic filters, such as photostability, non-irritability and broad spectrum protection. Nevertheless, inorganic filters have a whitening effect in sunscreen formulations owing to the high refractive index, decreasing their esthetic appeal. Many techniques have been developed to overcome this problem and among them, the use of nanotechnology stands out. The estimated amount of nanomaterial in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Skin cancer; Sunscreen; Inorganic UV filter.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000200002
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Sustainability, natural and organic cosmetics: consumer, products, efficacy, toxicological and regulatory considerations BJPS
Fonseca-Santos,Bruno; Corrêa,Marcos Antonio; Chorilli,Marlus.
The interest in sustainable products has increased along the years, since the choice of products, packaging and production processes have a great impact on the environment. These products are classified by regulatory agencies in different categories, aggregating advantages to the product and increasing the demand by consumers. However, there is no harmonization in guidelines of these certifying agencies and each cosmetic industry formulates their product and packaging in a more rational way, which causes less damage to the environment. Many cosmetic products have in their formulation natural products that perform a specific biological function, but these products should be evaluated on efficacy and toxicological aspects. The aim of this article is to...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Organic cosmetics; Natural cosmetics; Natural products; Sustainability; Cosmetics; Cosmetics.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000100017
Registros recuperados: 5
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